p53 is my shepherd, I shall not cycle

p53 is my shepherd, I shall not cycle

It maketh me to lie down in G1

It leadeth me beside still nucleotide pools

It restoreth my genome

It leadeth me past the restriction point for replication's sake

Even though I walk through the valley of the shadow of the cobalt irradiator

I shall fear no gamma rays, for thou art Guardian of the Genome

Thy amino and thy carboxy termini, they comfort me

Thou maintainest my genomic stability in the presence of mine enemies

Thou annointest my nucleus with p21/WAF1/Cip1/Sdi1/Pic1

my cyclin dependent kinases overflow

Surely pRb phosphorylation and E2F activation shall follow me

all the cycles of my life

and I shall dwell in a non-tumorigenic state until senescence

Via  Pharyngula